fatty degeneration of liver

The Preventive Effects of Bear Bile on Fatty Degeneration of Liver Cells in Guinea Pigs

熊胆粉对豚鼠肝脂肪变性的预防

Objective To determine whether bear bile could prevent fatty degeneration of liver cells caused by high fat diet and the mechanism .

目的探讨熊胆粉对高脂饮食豚鼠肝脂肪变性的预防及其作用机理。

Rat model of hydropic and fatty degeneration of liver were formed using complex disease-causing factors .

用复合致病因子制作大鼠肝细胞水样变性和脂肪变性动物模型；

Pathological histology is mainly expressed in fatty degeneration of liver cell injury and inflammatory cell infiltration .

病理组织学主要表现为脂肪变性、肝细胞损伤及炎症细胞浸润。

Results Bear bile could decrease the concentration of cholesterol in bile , raise the concentration of bile acid in bile and relieve fatty degeneration of liver .

结果熊胆粉能降低胆汁胆固醇浓度，提高胆汁胆汁酸浓度，缓解肝脂肪变性。

Were seen scattered in the lamivudine therapy mouse liver periportal lymphocyte infiltration , fibrous tissue hyperplasia , with mild fatty degeneration of liver cells around the central vein .

而拉米夫定治疗小鼠肝组织汇管内见散在的淋巴细胞浸润，无纤维组织增生，但中央静脉周围肝细胞轻度脂肪变性。

The results showed that Rad ix Rhod od end ri Mollis can cause focal necrosis , edema , ballooning degeneration and fatty degeneration of liver cells .

实验发现闹羊花根可致家犬肝灶状坏死，肝细胞水肿、气球样变性、脂肪变性；

C. intybus can significantly inhibit serum ALT , AST , fatty degeneration of liver cells and reduce the infiltration of inflammatory cells , that indicated it has the protection effect of the liver cells . 2 .

结果1.菊苣可显著抑制血清ALT、AST，减轻肝细胞脂肪变性及炎性细胞浸润，说明菊苣具有抑制肝细胞、肝损伤的作用。

Results The fatty degeneration of liver was basically recovered to normal and the liver contents of MDA , SOD , GSH , Vit E , TC and TG returned to near normal range in GZT treatment group .

结果：肝脂片组的肝组织脂肪变性基本恢复正常，同时肝内TC和TG含量，及肝内SOD、MDA、GSH和VitE含量恢复到接近正常。

Result : Histopathology revealed serious fatty degeneration of liver , fatty liver and the onset of hepatitis , fibrosis and cirrhosis . Along with the time progress , in islet gradually atrophic and accompanied by inflammatory infiltration . Fat cells gradually increased and with inflammatory infiltration .

结果：病理组织学显示肝脏发生严重的脂变、脂肪肝进而发生肝炎、纤维化及肝硬化；随时间进展胰岛逐渐萎缩并伴有炎性浸润；脂肪细胞逐渐增大并伴有炎性浸润。

Model + normal diet group rat liver tissue visible moderate to severe diffuse fatty degeneration of the liver tissue damage and fat deposition .

模型+普通饲料组大鼠肝脏组织可见中度到重度弥漫性脂肪变性，肝脏组织已经出现损害，有脂肪沉积情况。

An overload of ethanol over a long period of time produces fatty liver , a degeneration of liver tissue .

过量的乙醇，经长时间积累，将使肝组织退化而产生脂肪肝。

Formalin immersing organization will be used in paraffin-embedded , serial sections , the HE staining was to assess the degree of fatty degeneration and inflammatory response of liver tissues .

将福尔马林浸泡的组织，用石蜡包埋，连续切片，行HE染色观察肝细胞脂肪变性程度和肝组织炎症反应程度。

The first hit is fatty degeneration and lipid accumulation of liver cells induced by insulin resistance , and the second hit refers to the inflammation and necrosis of liver cells caused by oxidative stress and lipid peroxidation on the basis of the first hit .

该学说认为，NAFLD的初次打击是指由胰岛素抵抗引起的肝细胞脂肪变性及肝内脂肪沉积，而在此基础上发生的氧化应激及脂质过氧化反应所导致的肝脏发生炎症、坏死为二次打击。

Non-alcoholic fatty liver disease , mainly refers to the liver lipid metabolism disorders as a result of fatty degeneration of liver cells and fat piling up the clinicopathologic syndrome characterized .

非酒精性脂肪性肝病，主要是指由于肝脂质代谢障碍而导致肝细胞脂肪变性和脂肪贮积为特征的临床病理综合征。